Novel Fecal Biomarkers That Precede Clinical Diagnosis of Ulcerative Colitis
نویسندگان
چکیده
منابع مشابه
Fecal leukocyte in the diagnosis of ulcerative colitis.
A 57-year-old woman visited to our hospital because of lowgrade fever, vague lower abdominal discomfort and frequent small amount of blood-stained mucus with tenesmus for three weeks. She suffered from occasional severe abdominal cramping, and felt severe tenderness in anal canal on rectal examination, suggesting of proctitis. Laboratory findings were normal except for the elevation of CRP (3 m...
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Variation in clinical evidence has prevented the adoption of fecal microbiota transplantation (FMT) in patients with ulcerative colitis (UC). We aimed to conduct a systematic review and meta-analysis to determine the efficacy and safety of FMT in UC.A systematic literature search was performed in 5 electronic databases from inception through September 2015. Inclusion criteria were reports of FM...
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Objective. To explore fecal calprotectin levels in pediatric ulcerative colitis (UC) in relation with the validated clinical activity index PUCAI. Methods. This study included all 37 children (median age 14 years) with UC who had calprotectin measured (PhiCal ELISA Test) by the time of PUCAI assessment at the Children's Hospital of Helsinki in a total of 62 visits. Calprotectin values <100 μ g...
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BACKGROUND Although the etiology of idiopathic ulcerative colitis (UC) remains poorly understood, the intestinal flora is suspected to play an important role. Specific, consistent abnormalities in flora composition peculiar to UC have not yet been described, however Clostridium difficile colitis has been cured by the infusion of human fecal flora into the colon. This approach may also be applic...
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AIM To investigate the changes in microbiota in feces of patients with ulcerative colitis (UC) and pouchitis using genomic technology. METHODS Fecal samples were obtained from UC patients with or without an ileal pouch-anal anastomosis (IPAA) procedure, as well as healthy controls. The touchdown polymerase chain reaction technique was used to amplify the whole V3 region of the 16S rRNA gene, ...
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ژورنال
عنوان ژورنال: Gastroenterology
سال: 2021
ISSN: 0016-5085
DOI: 10.1053/j.gastro.2020.12.004